The Sindi Lab
at the University of California, Merced

Welcome to the Sindi Lab

Dr. Sindi is an Associate Professor in Applied Mathematics at at the University of California, Merced. The Sindi Lab focuses on mathematical and computational modeling of complex biological processes using both traditional applied mathematics methods and machine learning. Specifically, we are interested in the following:

  • Multi-scale dynamics of prion aggregate dynamics in yeast

  • Sensitivity analysis and uncertainty quantification in blood coagulation

  • Identification of genomic structural variants from high throughput sequencing data

  • Modeling and analysis of cell fate decisions with single-cell sequencing data

  • Genome evolution and population genetics


The Sindi Lab collaborates with several faculty at UC Merced including:

  • Dr. Rick Dale, Cognitive Science and Dr. David Ardell, QSB: Emergence and evolution of linguistic phenomena

  • Dr. Aaron Hernday and Dr. Clarissa Nobile, Biology: Dynamics and Genomics of Yeast

  • Dr. Katrina Hoyer, RNA-seq Analysis in Systemic Autoimmune Disorders

  • Dr. Roummel Marcia, Applied Mathematics: Mathematical optimization and computational genomics.

The Sindi Lab has long standing collaborations with outside researchers including:

  • Dr. Karin Leiderman, Colorado School of Mines: Protein diffusion and blood coagulation dynamics

  • Dr. Laurent Pujo-Menjouet, Lyon: Mathematical Biology, Prion Dynamics

  • Dr. Tricia R. Serio, University of Massachusetts, Amherst: Yeast prion biology

Sindi Lab Retreat at Mercer Caverns
Summer 2019