Dr. Sindi is a Professor in Applied Mathematics at at the University of California, Merced and the current Chair of the Applied Mathematics Department. The Sindi Lab focuses on mathematical and computational modeling of complex biological processes using both traditional applied mathematics methods and machine learning. Specifically, we are interested in the following:
Multi-scale dynamics of prion aggregate dynamics in yeast
Sensitivity analysis and uncertainty quantification in blood coagulation
Identification of genomic structural variants from high throughput sequencing data
Modeling and analysis of cell fate decisions with single-cell sequencing data
Genome evolution and population genetics
The Sindi Lab collaborates with several faculty at UC Merced including:
Dr. Aaron Hernday and Dr. Clarissa Nobile, Biology: Dynamics and Genomics of Yeast
Dr. Katrina Hoyer, RNA-seq Analysis in Systemic Autoimmune Disorders
Dr. Roummel Marcia, Applied Mathematics: Mathematical optimization and computational genomics.
The Sindi Lab has long standing collaborations with outside researchers including:
Dr. Mikahl Banwarth-Kuhn, California State Univeristy Easy Bay: Protein aggregation and agent based modeling
Dr. Karin Leiderman, University of North Carolina: Protein diffusion and blood coagulation dynamics
Dr. Laurent Pujo-Menjouet, Lyon: Mathematical Biology, Prion Dynamics
Dr. Tricia R. Serio, Univeristy of Washington, Yeast prion biology